Research Ethics Committee

Which ethics committee should I apply to?

There are currently the following different application routes for UCL staff and students whose projects require research ethics approval:

  1. NHS Research Ethics Review – any research that involves NHS patients and carers, invasive research involving prisoners or adults lacking capacity, a Clinical Trial of an Investigational Medicinal Product or human tissue. Please refer to → HRA checklist, → the HRA’s decision tool.
  2. Social Care Research Ethics Committee (SCREC) – ethical approval is required through SCREC for social care research projects funded by the → Department of Health.
  3. Ministry of Defence Research Ethics Committee (MoDREC) – ethical approval is required through → MoDREC for research involving human participants either undertaken, funded or sponsored by MOD in order to meet nationally and internationally accepted ethical standards.
  4. University Ethics Review – If your research does not fall into the above categories and it involves human participants, their tissue and/or data should apply to one of the following two ethics committees at UCL:
    UCL Research Ethics Committee – for all UCL staff and students
    UCL Institute of Education Research (IoE) Ethics Committee – for all IoE staff, students and visitors. The Institute maintains its own REC and policy separate from the UCL REC. For the Institute, all research projects which collect or use data from human participants including secondary data analysis and systematic reviews require ethical approval before the project starts. This includes preliminary and pilot studies. → Further details.

If you are unsure about the type of ethical review that is required please email: for advice.

R&D Approval
It should be noted that some studies that fall outside of the review requirements of the UK Health Departments' Research Ethics Service will still also require approval/management permission from the host care organisations, often called R&D approval. For all UCLH, RFH and Institute of Neurology staff undertaking medical research the → Joint Research Office provides all the information for i) R and D approval at UCLH; ii) Research contracts with UCLH both commercial and non-commercial; iii) for research governance and keeping your study legal; iv) training and education in research governance; v) collaborations with statisticians.

Please note that Multi Research Ethics Committee (MREC) approval may be necessary if it is a multi-centre study (i.e. involving more than one research site).

The UCL Research Ethics Committee

Ethical approval is required through the UCL REC if a specific research project is:

to ensure that the research conforms with general ethical principles and standards unless:

  1. the only involvement of human participants in particular research activities will be one or more of the categories listed in our → exemptions in which case the research will be EXEMPT from ethics approval unless approval is specifically required by an external funding body or other external body in order to obtain research permission;
  2. UCL staff are involved as co-researchers in a project led by a Principal Researcher from another UK institution and ethics approval has been granted by that institution. Please note that for studies conducted overseas, ethical approval from both a UK and a local institution is required.

If research is exempt from formal approval under the following criteria, it is still expected that UCL researchers will abide by the appropriate ethical guidelines of their discipline.

Department Heads have final judgment as to whether a particular activity should be exempt from the requirement for approval by the UCL Ethics Committee. But note that the exemptions do not apply to research involving vulnerable participants as defined in our guidelines.

Exemption from approval by the UCL Ethics Committee DOES NOT IMPLY that the research is also exempt from registration with the UCL Data Protection Officer nor from UCL Risk Assessment procedures.

If your study is not exempt from ethical approval you will need to submit an application to the UCL Research Ethics Committee. Please follow the steps on our → Procedures for Applicants page.